Introduction.- Sources of redox active secondary metabolites.- The modern art of identification of natural substances in whole plants (I).- A word on redox activity.- Oxidative stress, antioxidants, chemoprevention and beneficial roles of pro-oxidants.- The French paradox at Tea time: From flavonoids toward synthetic stilbene-based drugs.- Bio reactivity of resveratrol in relation to inflammatory processes; Norbert Latruffe.- Treasures along the oligomeric road from flavonoids to polyphenols and tannins.- The cellular thiolstat as emerging target of secondary metabolites.- Thiosulfinates, organic polysulfanes and related compounds: From an unusual chemistry toward a wealth of potential applications.- Beyond glutathione:- Different low molecular weight thiols as mediators of redox regulation and other metabolic functions in lower organisms.- Garlic based natural products: Turning secondary plant metabolites into a commercial success.- Phytol, a chlorophyll component with anti-inflammatory properties.- Recent advances in molecular genetics of furanocoumarin synthesis in higher plants.- Natural products molten together: Towards multifunctional hybrid molecules with specific activities and applications.- Nanotaxis for antioxidants.- Industrial uses of redox active enzymes.- Systemic enzyme therapy Fact or Fiction.- Conclusions and outlook.