The International Scientific and Technical Conference "Integrated Computer Technologies in Mechanical Engineering" - Synergetic Engineering (ICTM) was established by National Aerospace University "Kharkiv Aviation Institute". The Conference ICTM'2021 was held in Kharkiv, Ukraine, during October 28-29, 2021. During this conference, technical exchanges between the research community were carried out in the forms of keynote speeches, panel discussions, as well as special session. In addition, participants were treated to a series of receptions, which forge collaborations among fellow researchers. ICTM'2021 received 203 papers submissions from different countries. Target Groups ICTM was formed to bring together outstanding researchers and practitioners in the field of information technology in the design and manufacture of engines; creation of rocket space systems, aerospace engineering from all over the world to share their experience and expertise.