Electroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.

1) Introductory 1 Introduction to Electroporation Edward W. Lee, Julie Gehl, Stephen T. Kee 2 Electroporation and cellular physiology Hanne Gissel, Raphael C. Lee, Julie Gehl 3 The cell in the electric field Tadej Kotnik, Gorazd Pucihar, Damijan Miklavčič 4 Understanding Electric Fields for Clinical Use Faisal Mahmood 5 Generators and Applicators - Equipment for Electroporation Lasse Staal, Richard Gilbert 2)Electrochemotherapy   6 Cell electropermeabilization and cellular uptake of small molecules: the electrochemotherapy concept Aude Silve, Lluis M. Mir 7 Vascular-disrupting action of electrochemotherapy: mode of action and therapeutic implications Gregor Sersa, Maja Cemazar 8 Electrochemotherapy of small tumors; the experience from the ESOPE (European Standard Operating Procedures for Electrochemotherapy) group Gregor Sersa, Julie Gehl, Jean-Remy Garbay, Declan Soden, Gerald C. O¿Sullivan, Louise W. Matthiessen, Marko Snoj, Lluis M. Mir 9 Electrochemotherapy for larger malignant tumors Louise W. Matthiessen, Tobian Muir, Julie Gehl 10 Cell electroporation in bone tissue Fini M, Tschon M, Alberghini M, Bianchi G, Mercuri M, Campanacci L, Cavani F, Ronchetti M, De Terlizzi F, Cadossi R 11 Drug and Gene electrotransfer to the brain Birgit Agerholm-Larsen, Mette Linnert, Helle K. Iversen,  Julie Gehl 12 Minimally invasive intraluminal tumor ablation Patrick F Forde, Michael G Bourke, Slawomir Salwa, Gerald C O¿ Sullivan, Declan M Soden 3) Gene Electrotransfer   13 Electrotransfer of plasmid DNA J.M. Escoffre, M.P. Rols, David A. Dean 14 Gene Electrotransfer to Tumor Loree C. Heller, Richard Heller 15 Gene electrotransfer to lung David A. Dean 16 Gene electrotransfer to muscle tissue; moving into clinical use Pernille Hojman17 Gene electrotransfer to skin Anita Gothelf, Julie Gehl 18 Electroporation-mediated DNA vaccination Paolo Fagone, Devon J. Shedlock, Stephen Kemmerer , Dietmar Rabussay,  David B. Weiner 4) Irreversible Electroporation   19 Irreversible Electroporation (IRE) on Liver Tumor Ablation: A Summary of Preclinical Translational Research Edward W. Lee, Daphne Wong, Stephen T. Kee 20 Translational Research on Irreversible Electroporation - VX2 Rabbit Head and Neck Daphne Wong, Edward W. Lee, Cassidy H. Tran, Stephen T. Kee 21 Clinical Research on Irreversible Electroporation of the Liver Ken Thomson, Stephen T. Kee